Which is more popular, Microsoft Agent Framework or Agno?

Agno has more GitHub stars (42,416 vs 13,883).

Which is more actively developed, Microsoft Agent Framework or Agno?

Microsoft Agent Framework had more commits in the last 90 days (910 vs 352).

Should I use Microsoft Agent Framework or Agno?

Compare their capabilities, limitations and "best for" notes above. Both are open source, so trying each on a small task is the fastest way to decide.

Microsoft Agent Framework vs Agno

Side-by-side comparison of two AI agent tools

Microsoft Agent Frameworkopen-source

A framework for building, orchestrating and deploying AI agents and multi-agent workflows with support for Python and .NET.

Agnoopen-source

Build, run, manage agentic software at scale.

Metrics

	Microsoft Agent Framework	Agno
Stars	13.9k	42.4k
Star velocity /mo	1.2k	551.7112299465241
Commits (90d)	910	352
Releases (6m)	10	10
Overall score	0.8076639330110338	0.7409951578552401

Pros

+Production-ready runtime with built-in scalability, session isolation, and native tracing capabilities
+Comprehensive monitoring and management through AgentOS UI for testing, debugging, and production oversight
+Simple development experience - build sophisticated agents with memory and tools in approximately 20 lines of Python code

Cons

-Python-focused platform with limited examples for other programming languages
-Requires multiple dependencies and proper configuration of API keys and database connections
-May have a learning curve for implementing complex multi-agent workflows and team coordination

Use Cases

•Building production AI agents with persistent state, memory, and custom tool integrations for customer service or automation
•Creating multi-agent teams and workflows for complex business processes that require coordination between specialized agents
•Enterprise deployment of AI agents with comprehensive monitoring, user session management, and production-grade reliability requirements

View Microsoft Agent Framework Details View Agno Details

FAQ

Which is more popular, Microsoft Agent Framework or Agno?: Agno has more GitHub stars (42,416 vs 13,883).
Which is more actively developed, Microsoft Agent Framework or Agno?: Microsoft Agent Framework had more commits in the last 90 days (910 vs 352).
Should I use Microsoft Agent Framework or Agno?: Compare their capabilities, limitations and "best for" notes above. Both are open source, so trying each on a small task is the fastest way to decide.